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Stem cells can be used in treatments for many different types of diseases. One of the main places young stem cells are found is in cord blood, which can be stored at birth and saved for future use if needed. Stem cells are also found in other places in the human body, including blood and bone marrow.
Started the National Cord Blood Inventory (NCBI). The goal of the NCBI is to collect and store at least 150,000 new cord blood units. These cord blood units are used for patients who need a transplant but do not have a matching donor within their family. To continue to help the success of transplants, the NCBI banks will provide additional cord blood units for research.
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CBR collection kits have been designed to shield the samples from extreme temperatures (shielding for more than 1 hour at extreme hot and cold). Samples remain at room temperature and are shipped directly to the CBR lab for processing.
Donating your baby’s cord blood to a public bank is always free. The limitations of the public banking network in the United States are: they only collect donations at large birthing hospitals in ethnically diverse communities, the mother must pass a health screening, they prefer registration by 34 weeks of pregnancy, and they only save the largest cord blood collections. The potential reward of public donation is that your baby could Be The Match to save a life!
The term “cord blood” is used for the blood remaining in the umbilical cord and the placenta after the birth of a baby. Cord Blood contains stem cells that can grow into blood and immune system cells, as well as other types of cells. Today cord blood is often used as a substitute for bone marrow in stem cell transplants. There are over 80 diseases treated this way, including cancers, blood disorders, genetic and metabolic diseases.
The cord is cut and clamped, just like normal. The mother doesn’t go through anything different during birth, and neither does her child. They will experience no additional pain or procedures before, during, or after birth.
Checked to make sure it has enough blood-forming cells for a transplant. (If there are too few cells, the cord blood unit may be used for research to improve the transplant process for future patients or to investigate new therapies using cord blood, or discarded.)
A limitation of cord blood is that it contains fewer HSCs than a bone marrow donation does, meaning adult patients often require two volumes of cord blood for treatments. Researchers are studying ways to expand the number of HSCs from cord blood in labs so that a single cord blood donation could supply enough cells for one or more HSC transplants.
Expectant families interested in donating can call 1-800-KARMANOS (1-800-527-6266). Potential donors will be provided with general information regarding the donation process. Staff will be available to answer any questions or concerns you may have along the way.
The parents who make the decision to store their baby’s cord blood and cord tissue are thinking ahead, wanting to do right from the start (even before the start), and taking steps to do whatever they can to protect their baby down the road. Today, many conscientious parents are also considering delayed cord clamping (DCC), a practice in which the umbilical cord is not clamped immediately but rather after it continues to pulse for an average of 30 seconds to 180 seconds. Many parents don’t realize that they can delay the clamping of the cord and still bank their baby’s cord blood. As noted early, our premium processing method, PrepaCyte-CB, is able to capture more immune system cells and reduce the greatest number of red blood cell contaminants. This makes it go hand in hand with delayed cord clamping because it is not as affected by volume, effectively making up for the smaller quantity with a superior quality. You can read more about delayed cord clamping vs. cord blood banking here.
Finally, the healthy stem cells are placed into long-term cryogenic storage. Compared to other stem cell sources, cord blood units are available very quickly since a doctor can remove them from storage and send them to the transplant hospital within a few days.
The chances of a successful bone marrow or cord blood transplant are better when the blood-forming cells are from a donor who closely matches the patient. However, studies show that cord blood may not need to match as closely as is necessary for a marrow donor. Umbilical cord blood may be especially promising for:
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Your adult cells have one disadvantage to cord blood cells – they cannot change their cell type. When stem cells from cord blood and tissue are transplanted, they adjust to fit the individual patient and replace damaged cells. Adult stem cells are also older, which means they have been exposed to disease, and may damage patients after the transplant. Compared to cord blood cells, adult cells have a higher chance for graft-versus-host disease.
Women typically sign up for cord blood banking between the 28th and 34th week of pregnancy. Some private banks will allow for early or late sign up, but most public storage facilities won’t accept any mother past her 34th week. While most banks don’t officially sign up mothers until a certain time, it’s never too early to research.
Cord Blood Registry is headquartered in South San Francisco, California. CBR owns their 80,000 square foot laboratory located in Tucson, Arizona. CBR’s laboratory processes cord blood collections seven days a week, 365 days a year. The state-of-the-art facility has the capacity to store the stem cell samples of five million newborns.
Through these two means, we are always producing more cells. In fact, much of your body is in a state of constant renewal because many cells can live for only certain periods of time. The lifespan for a cell in the stomach lining is about two days. Red blood cells, about four months. Nerve and brain cells are supposed to live forever. This is why these cells rarely regenerate and take a long time if they do.
One part of the Program, the Cord Blood Coordinating Center, has a network of cord blood banks, including some banks that get Federal support to build the NCBI. The Cord Blood Coordinating Center works with its network of cord blood banks to recruit expectant parents for umbilical cord blood donations and to distribute cord blood units listed on the registry of the C.W. Bill Young Cell Transplantation Program, also called the Be The Match Registry®. The registry is a listing of potential marrow donors and donated cord blood units.
Cord blood banking is the process of collecting and storing your baby’s umbilical cord blood stem cells for potential medical use. ViaCord also offers parents the option to collect and store stem cells found in the tissue of the umbilical cord. This is known as cord tissue banking. Our approach to cord blood and cord tissue banking is simple: Apply the most advanced science to deliver the highest-quality stem cell collection and storage process in order to achieve the best results for families. That approach has guided our growth and success for nearly twenty-five years.
Once you arrive at the hospital, all you need to worry about is having a safe birth. There are a few minor things that you and your family must remember at the hospital, but your priority should be birth and spending time with your newborn.
Cord Blood Registry is a registered trademark of CBR® Systems, Inc. Annual grant support for Parent’s Guide to Cord Blood Foundation is made possible by CBR® through the Newborn Possibilities Fund administered by Tides Foundation.
AutoXpress™ Platform (AXP) cord blood processing results in a red-cell reduced stem cell product. Each sample is stored in a cryobag consisting of two compartments (one major and one minor) and two integrally attached segments used for unit testing.
There are usually two fees involved in cord blood banking. The first is the initial fee that covers enrollment, collection, and storage for at least the first year. The second is an annual storage fee. Some facilities vary the initial fee based upon the length of a predetermined period of storage.